Opsonization of HIV-1 by Semen Complement Enhances Infection of Human Epithelial Cells
نویسندگان
چکیده
منابع مشابه
Opsonization of HIV-1 by semen complement enhances infection of human epithelial cells.
In the present study we demonstrate that both X4- and R5-tropic HIV-1 strains are able to infect the human epithelial cell line HT-29. Infection was enhanced 2-fold when HIV was added to semen before contact with the cell cultures. The enhancing effect of semen was complement dependent, as evidenced by blockage of generation of C3a/C3a(desArg) in semen by heat or EDTA treatment of semen and sup...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2002
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.169.6.3301